SCHEMBL15069507

SCHEMBL15069507

O=C(O)C(C(=O)O)C1CCC2OC2C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TFPI2 P48307 7/20 0.43
GMNN O75496 2/20 0.43
LMNA P02545 2/20 0.43
PMP22 Q01453 2/20 0.43
TP53 P04637 2/20 0.43
NFKB1 P19838 2/20 0.43
THPO P40225 2/20 0.43
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43
PPM1B O75688 3/20 0.36
PTPN1 P18031 2/20 0.33
PPP1CC P36873 2/20 0.33
PPP5C P53041 2/20 0.33
PPP2CA P67775 1/20 0.33
NPY4R P50391 1/20 0.33
MAPK1 P28482 2/20 0.30
CYP2C19 P33261 1/20 0.30
STAT6 P42226 1/20 0.30
HIF1A Q16665 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28379991 0.81 SLC1A2 (0.34) LMNAPMP22KDM4ECYP2C19
SCHEMBL5616701 0.75 CPN1 (0.33) LMNATP53KDM4ETSHRCYP2C19
SCHEMBL1645240 0.75 CPN1 (0.33) LMNATP53KDM4ETSHRCYP2C19
SCHEMBL25353670 0.75 TFPI2 (0.36) TFPI2GMNNLMNAPMP22TP53
SCHEMBL13353720 0.75 EPHX1 (0.42) TFPI2GMNNLMNAPMP22TP53
SCHEMBL27518471 0.75 SLC1A2 (0.31)
SCHEMBL5358088 0.74 TFPI2 (0.39) TFPI2GMNNLMNAPMP22TP53
SCHEMBL8407085 0.72 KDM4E (0.34) TFPI2GMNNLMNAPMP22TP53
SCHEMBL7760106 0.72 KDM4E (0.33) TFPI2GMNNLMNAPMP22TP53
SCHEMBL6908695 0.72 EPHX1 (0.36) TP53KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797980-A1 FUNCTIONAL SILANE-COMPATIBILIZED EPOXY COMPOSITIONS FOR INSULATION APPLICATIONS Dow Global Technologies LLC (US) 2014-11-05 EP disclosed
WO-2013097197-A1 FUNCTIONAL SILANE-COMPATIBILIZED EPOXY COMPOSITIONS FOR INSULATION APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed