SCHEMBL8407085

SCHEMBL8407085

O=C(O)C(CC1CCC2OC2C1)C1CCC2OC2C1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
PMP22 Q01453 1/20 0.34
TFPI2 P48307 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
PPM1B O75688 1/20 0.33
CPN1 P15169 2/20 0.31
CPB2 Q96IY4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134091 0.81
SCHEMBL25353670 0.79 TFPI2 (0.36) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL28513029 0.78 KDM4E (0.35) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL4306628 0.76 CPN1 (0.34) PPM1BCPN1CPB2
SCHEMBL16217677 0.74
SCHEMBL16217682 0.74
SCHEMBL9002916 0.74 PPM1B (0.43) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL4641432 0.73 TP53 (0.33) TP53PPM1BCPN1CPB2
SCHEMBL15069507 0.72 TFPI2 (0.43) KDM4EGMNNLMNAPMP22TFPI2
Bicarbonate SCHEMBL2015874 0.72 TFPI2 (0.43) KDM4EGMNNLMNAPMP22TFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297258-A Non-yellowing paint formulations containing iodo substituted alkynyl urethanes as fungicides ICI AMERICAS INC. (US) 1981-10-27 US claimed
US-6008266-A INCLUDES AN EPOXY MONOMER OF GIVEN FORMULA WHICH IS CURABLE USING ACTINIC RADIATION AND INCORPORATES A CLEAVABLE ACETAL LINKAGE WHICH RENDERS THE CURED EPOXY FORMULATIONS SOLUBLE IN DILUTE ACID, TO ALLOW RECOVERY FOLLOWING CURE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-12-28 US disclosed
EP-0556810-B1 Color filter array element with protective overcoat layer and method of forming same EASTMAN KODAK CO (US) 1996-05-22 EP disclosed
EP-0556810-A1 Color filter array element with protective overcoat layer and method of forming same EASTMAN KODAK COMPANY (US) 1993-08-25 EP disclosed
US-5166126-A Image heating a dye donor on a radiation transparent support, coating and photopolymerization for electrooptical displays EASTMAN KODAK COMPANY (US) 1992-11-24 US disclosed