SCHEMBL15069748

SCHEMBL15069748

CCCC[C@H](O)[C@@H](NC(=O)O)c1ccc(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15067571 1.00 CNR1 (0.41) CNR1CNR2TAS1R3TAS1R1MMP2
SCHEMBL15067436 1.00 CNR1 (0.41) CNR1CNR2TAS1R3TAS1R1MMP2
SCHEMBL15066249 0.87 TAS1R3 (0.45) TAS1R3TAS1R1MEN1KMT2A
SCHEMBL16054408 0.87 TAS1R3 (0.45) TAS1R3TAS1R1MEN1KMT2A
SCHEMBL15069770 0.87 TAS1R3 (0.45) TAS1R3TAS1R1MEN1KMT2A
SCHEMBL15066231 0.79 MEN1 (0.48) ALDH1A1MEN1KMT2APOLBL3MBTL1
SCHEMBL15066567 0.79 MEN1 (0.48) ALDH1A1MEN1KMT2APOLBL3MBTL1
SCHEMBL15066855 0.79 MEN1 (0.48) ALDH1A1MEN1KMT2APOLBL3MBTL1
SCHEMBL253969 0.78 LMNA (0.43) CNR1CNR2ALDH1A1MAPK1MEN1
SCHEMBL29528426 0.78 LMNA (0.43) CNR1CNR2ALDH1A1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111419830-B Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes 比皮艾思药物研发有限公司 2024-01-30 CN disclosed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN disclosed
CN-111419830-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes 比皮艾思药物研发有限公司 2020-07-17 CN disclosed
EP-2968211-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME Bio-Pharm Solutions Co., Ltd. (KR) 2016-01-20 EP disclosed
EP-2797881-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2014142519-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed