Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069841 | 0.84 | PSEN1 (0.34) | — | |
| SCHEMBL30078116 | 0.84 | PSEN1 (0.34) | — | |
| SCHEMBL30077997 | 0.81 | NUDT1 (0.40) | PRKCINUDT1PIK3C3 | |
| SCHEMBL15068357 | 0.81 | NUDT1 (0.40) | PRKCINUDT1PIK3C3 | |
| SCHEMBL30077966 | 0.80 | PSEN1 (0.34) | — | |
| SCHEMBL15065743 | 0.80 | PSEN1 (0.34) | — | |
| SCHEMBL30078149 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL15065242 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL20579824 | 0.72 | CYP1A2 (0.33) | — | |
| SCHEMBL15065651 | 0.71 | PTGER1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797597-A1 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2014-11-05 | — | — | EP | claimed |
| WO-2013102145-A1 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | claimed |