⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14793882 | 0.81 | — | — | |
| SCHEMBL15069886 | 0.81 | — | — | |
| SCHEMBL27140050 | 0.81 | RORC (0.30) | — | |
| SCHEMBL15071361 | 0.77 | GAA (0.31) | — | |
| SCHEMBL15069881 | 0.77 | TMEM97 (0.30) | — | |
| SCHEMBL12251588 | 0.69 | GAA (0.52) | — | |
| SCHEMBL25957585 | 0.69 | PPARA (0.30) | — | |
| SCHEMBL27152835 | 0.67 | CNR1 (0.32) | — | |
| SCHEMBL27152833 | 0.67 | LMNA (0.31) | — | |
| SCHEMBL14788263 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403815-B2 | Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-08-02 | — | — | US | disclosed |
| US-20130165416-A1 | COMPOUNDS AND USES THEREOF IN MODULATING LEVELS OF VARIOUS AMYLOID BETA PEPTIDE ALLOFORMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2013-06-27 | — | — | US | disclosed |