Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 17/20 | 0.68 |
| ▸ | RARB | P10826 | 17/20 | 0.68 |
| ▸ | RARG | P13631 | 16/20 | 0.68 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775415 | 0.96 | RARA (0.63) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327701 | 0.90 | RARA (0.68) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL18775432 | 0.86 | RARB (0.73) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL12444486 | 0.86 | RARA (0.73) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL18775433 | 0.84 | RARA (0.51) | RARARARBRARGRXRACYP3A4 | |
| SCHEMBL17327714 | 0.83 | RARB (0.62) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327722 | 0.82 | RARA (0.67) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327788 | 0.82 | RARA (0.67) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL2331952 | 0.81 | RARB (1.00) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL10835249 | 0.81 | RARB (0.79) | RARARARBRARGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114019-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC. | 2017-04-27 | — | — | US | disclosed |
| US-20130165520-A1 | Hybrid Molecule Having Mixed Retinoic Acid Receptor Agonism and Histone Deacetylase Inhibitory Properties | UNIVERSITY DE MONTREAL (CA) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165520-A1 | Hybrid Molecule Having Mixed Retinoic Acid Receptor Agonism and Histone Deacetylase Inhibitory Properties | RARA, RARG, RARB | RARA 1/4885RARB 3/4885RARG 2/4885 |
| US-20170114019-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | CKMT1A; CKMT1B, MYLK2, CPT1B | RARA 1809/4885RARB 1026/4885RARG 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.