Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 17/20 | 0.68 |
| ▸ | RARB | P10826 | 17/20 | 0.68 |
| ▸ | RARG | P13631 | 16/20 | 0.68 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070047 | 0.90 | RARA (0.68) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL18775415 | 0.86 | RARA (0.63) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL12444486 | 0.86 | RARA (0.73) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL18775432 | 0.83 | RARB (0.73) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327714 | 0.83 | RARB (0.62) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327722 | 0.82 | RARA (0.67) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL2331952 | 0.81 | RARB (1.00) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL10835249 | 0.81 | RARB (0.79) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327787 | 0.80 | RARB (0.58) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL17327788 | 0.80 | RARA (0.67) | RARARARBRARGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015188015-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC. (US) | 2015-12-10 | — | — | WO | disclosed |