Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070139 | 0.78 | GAA (0.34) | GAAALDH1A1POLBMAPTKMT2A | |
| SCHEMBL18879900 | 0.69 | GAA (0.30) | GAATSHR | |
| SCHEMBL15833350 | 0.67 | CYP3A4 (0.40) | GAAPOLBKMT2A | |
| SCHEMBL20795953 | 0.65 | GAA (0.36) | GAAALDH1A1KMT2ATSHRBCHE | |
| SCHEMBL15841115 | 0.65 | — | — | |
| SCHEMBL21015425 | 0.65 | ALDH1A1 (0.36) | GAAALDH1A1KMT2ATSHR | |
| SCHEMBL15070138 | 0.64 | — | — | |
| SCHEMBL18477453 | 0.62 | P2RY2 (0.38) | GAAPOLBKMT2A | |
| SCHEMBL15841134 | 0.62 | GAA (0.33) | GAAALDH1A1KMT2ATSHR | |
| SCHEMBL24062790 | 0.61 | LGALS9 (0.43) | GAAALDH1A1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092481-A1 | 2',4'-DIFLUORO-2'-METHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | F. HOFFMANN-LA ROCHE AG (CH) | 2013-06-27 | — | — | WO | disclosed |