SCHEMBL15070596

SCHEMBL15070596

C=C(C)C(=O)OC[Si](O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 3/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4583359 0.86 TSHR (0.50) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL9170187 0.84 TSHR (0.48) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL269321 0.81 TSHR (0.50) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL1806299 0.79 TSHR (0.48) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL12094993 0.79 TSHR (0.48) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL332509 0.77 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL82401 0.77 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL21641726 0.77 THRB (0.53) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL22470059 0.77 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL7190871 0.77 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8565058-B2 Liquid crystal alignment film, process for its production, optical element using the liquid crystal alignment film, and optical information writing/reading device ASAHI GLASS COMPANY, LIMITED (JP) 2013-10-22 US disclosed
US-20130163399-A1 LIQUID CRYSTAL ALIGNMENT FILM, PROCESS FOR ITS PRODUCTION, OPTICAL ELEMENT USING THE LIQUID CRYSTAL ALIGNMENT FILM, AND OPTICAL INFORMATION WRITING/READING DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2013-06-27 US disclosed