Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14422632 | 0.91 | LMNA (0.49) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15071083 | 0.77 | LMNA (0.47) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL11591288 | 0.74 | ALDH1A1 (0.56) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL11591282 | 0.74 | ALDH1A1 (0.56) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL29325973 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL273013 | 0.73 | ALDH1A1 (0.55) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL7755993 | 0.73 | LMNA (0.55) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL273014 | 0.73 | ALDH1A1 (0.55) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL11591517 | 0.73 | LMNA (0.56) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL112071 | 0.73 | ALDH1A1 (0.55) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077361-B1 | USE OF CYCLOHEXANOIC ACID DERIVATIVES AS PLASTICIZERS | RUDOLPH THOMAS (CH) | 2019-06-12 | — | — | EP | disclosed |
| US-10071037-B2 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2018-09-11 | — | — | US | disclosed |
| US-RE46698-E1 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2018-02-06 | — | — | US | disclosed |
| US-RE46698-E1 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2018-02-06 | — | — | US | disclosed |
| US-RE46698-E1 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2018-02-06 | — | — | US | disclosed |
| CN-104010525-B | Cyclohexanol derivative as antibacterial anti-microbial active matter purposes | 默克专利股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| US-9492364-B2 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-9492364-B2 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-9492364-B2 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-20160326091-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-20160326091-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-20160326091-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| EP-3077361-A1 | USE OF CYCLOHEXANOIC ACID DERIVATIVES AS PLASTICIZERS | Merck Patent GmbH (DE) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015144328-A1 | SUNSCREEN ACTIVE-INGREDIENT COMBINATIONS CONSISTING OF PHENYLENE-1,4-BIS-(2-BENZIMIDAZYL)-3,3'-5,5'-TETRASULFONIC ACID AND/OR PHENYLENE-1,4-BIS-(2-BENZIMIDAZYL)-3,3'-5,5'-TETRASULFONIC ACID SALTS AND LOW-MOLECULAR PHENOL DERIVATES, AND COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ACTIVE-INGREDIENT COMBINATIONS | BEIERSDORF AG (DE) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015082034-A1 | USE OF CYCLOHEXANOIC ACID DERIVATIVES AS PLASTICIZERS | MERCK PATENT GMBH (DE) | 2015-06-11 | — | — | WO | disclosed |
| WO-2015082034-A1 | USE OF CYCLOHEXANOIC ACID DERIVATIVES AS PLASTICIZERS | MERCK PATENT GMBH (DE) | 2015-06-11 | — | — | WO | disclosed |
| US-20140335029-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140335029-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140335029-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| WO-2013091775-A2 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE INGREDIENTS | MERCK PATENT GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335029-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | CYP51A1, DDT, EBP | LMNA 4136/4885ALDH1A1 437/4885CYP3A4 115/4885 |
| US-10071037-B2 | Use of cyclohexanol derivatives as antimicrobial active compounds | CYP51A1, DDT, EBP | LMNA 4136/4885ALDH1A1 437/4885CYP3A4 115/4885 |
| US-20160326091-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | CYP51A1, DDT, EBP | LMNA 4136/4885ALDH1A1 437/4885CYP3A4 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.