SCHEMBL15071100

SCHEMBL15071100

Cc1nc2ccc(C(=O)N3CCCCC3)cn2c1-c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.77
HPGD P15428 10/20 0.51
MAPK1 P28482 2/20 0.51
CNR1 P21554 1/20 0.49
TSHR P16473 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
GBA1 P04062 1/20 0.45
AKT1 P31749 3/20 0.44
AKT2 P31751 3/20 0.44
ALDH1A1 P00352 4/20 0.44
LMNA P02545 1/20 0.44
USP2 O75604 1/20 0.44
SLC6A7 Q99884 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15071143 0.98 F2RL1 (0.74) F2RL1HPGDMAPK1CNR1TSHR
SCHEMBL15071152 0.92 F2RL1 (0.75) F2RL1HPGDMAPK1TSHRGBA1
SCHEMBL15071132 0.91 F2RL1 (0.64) F2RL1HPGDCNR1TSHRNPC1
SCHEMBL31518 0.89 F2RL1 (0.72) F2RL1HPGDMAPK1GBA1AKT1
SCHEMBL31560 0.89 F2RL1 (0.63) F2RL1HPGDMAPK1NPC1RAB9A
SCHEMBL15071138 0.88 F2RL1 (0.62) F2RL1HPGDMAPK1CNR1TSHR
SCHEMBL15071127 0.88 F2RL1 (0.62) F2RL1HPGDCNR1GBA1ALDH1A1
SCHEMBL15071130 0.88 F2RL1 (0.62) F2RL1HPGDCNR1NPC1RAB9A
SCHEMBL15050009 0.88 F2RL1 (0.68) F2RL1HPGDAKT1AKT2SLC6A7
SCHEMBL15071136 0.88 F2RL1 (0.62) F2RL1HPGDMAPK1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME F2RL1, F2R, FPR2 F2RL1 1/4885HPGD 80/4885MAPK1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.