SCHEMBL15071130

SCHEMBL15071130

Cc1nc2ccc(C(=O)N3CCCCC3)cn2c1-c1ccc(F)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.62
ADORA2A P29274 6/20 0.48
SLC2A1 P11166 1/20 0.45
GRM2 Q14416 2/20 0.44
DPP4 P27487 1/20 0.44
ENPP2 Q13822 1/20 0.44
GRM5 P41594 2/20 0.43
ALDH1A1 P00352 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PKM P14618 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.42
CLPP Q16740 1/20 0.42
CNR1 P21554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15071132 0.91 F2RL1 (0.64) F2RL1SLC2A1GRM5ALDH1A1NPC1
SCHEMBL15071138 0.89 F2RL1 (0.62) F2RL1ADORA2AALDH1A1NPC1RAB9A
SCHEMBL15071127 0.89 F2RL1 (0.62) F2RL1GRM5ALDH1A1KMT2AKDM4E
SCHEMBL15071143 0.89 F2RL1 (0.74) F2RL1SLC2A1NPC1RAB9AMEN1
SCHEMBL15071100 0.88 F2RL1 (0.77) F2RL1ALDH1A1NPC1RAB9AMEN1
SCHEMBL15071133 0.87 F2RL1 (0.60) F2RL1GRM5ALDH1A1NPC1RAB9A
SCHEMBL31488 0.85 F2RL1 (0.60) F2RL1ADORA2AALDH1A1NPC1RAB9A
SCHEMBL15071135 0.85 F2RL1 (0.58) F2RL1SLC2A1ALDH1A1NPC1RAB9A
SCHEMBL31560 0.82 F2RL1 (0.63) F2RL1DPP4GRM5ALDH1A1NPC1
SCHEMBL15071136 0.81 F2RL1 (0.62) F2RL1ADORA2AALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME F2RL1, F2R, FPR2 F2RL1 1/4885ADORA2A 1056/4885SLC2A1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.