SCHEMBL15071157

SCHEMBL15071157

Cc1nc2ccc(C(=O)N3CCC(O)(C4CCCCC4)CC3)cn2c1-c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.72
AKT1 P31749 12/20 0.42
AKT2 P31751 12/20 0.42
ATM Q13315 1/20 0.39
PKLR P30613 2/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
OPRL1 P41146 1/20 0.39
FASN P49327 1/20 0.38
GBA1 P04062 1/20 0.38
SLC2A1 P11166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15071100 0.85 F2RL1 (0.77) F2RL1AKT1AKT2GBA1
SCHEMBL31499 0.84 F2RL1 (0.62) F2RL1AKT1AKT2PKLRFASN
SCHEMBL31519 0.83 F2RL1 (1.00) F2RL1FASNSLC2A1
SCHEMBL15071143 0.83 F2RL1 (0.74) F2RL1AKT1AKT2GBA1SLC2A1
SCHEMBL15071155 0.82 F2RL1 (0.73) F2RL1AKT1AKT2FASN
SCHEMBL15071158 0.82 F2RL1 (0.73) F2RL1
SCHEMBL15071152 0.81 F2RL1 (0.75) F2RL1FASNGBA1SLC2A1
SCHEMBL15071151 0.81 F2RL1 (0.75) F2RL1AKT1AKT2FASNGBA1
SCHEMBL31491 0.81 F2RL1 (0.75) F2RL1AKT1AKT2FASNSLC2A1
SCHEMBL31526 0.80 F2RL1 (0.90) F2RL1FASNSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME F2RL1, F2R, FPR2 F2RL1 1/4885AKT1 669/4885AKT2 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.