SCHEMBL15071477

SCHEMBL15071477

Cc1cc(C(C)c2cc(C)c(O)c(C(C)c3cc(-c4ccccc4)ccc3O)c2)cc(C(C)c2cc(-c3ccccc3)ccc2O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
ESR2 Q92731 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HSP90AA1 P07900 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ACMSD Q8TDX5 3/20 0.36
HNF4A P41235 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51794 0.83 ALOX5 (0.57) ALOX5HSD17B1HSD17B2ESR2KDM4E
SCHEMBL24411334 0.81 HSD17B1 (0.40) ALOX5HSD17B1HSD17B2ESR2KDM4E
SCHEMBL15071480 0.81 TP53 (0.41) ALOX5MEN1KMT2ALMNAMAPT
SCHEMBL8984112 0.79 TYR (0.51) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL1500557 0.79 TYR (0.50) ALOX5ESR2KDM4EMEN1KMT2A
SCHEMBL16945398 0.78 HSD17B1 (0.53) ALOX5HSD17B1HSD17B2ESR2KDM4E
SCHEMBL1344700 0.76 TYR (0.47) ESR2KDM4EMEN1KMT2ALMNA
SCHEMBL5712112 0.76 TYR (0.47) ESR2KDM4EMEN1KMT2ALMNA
SCHEMBL24411454 0.76 HSD17B1 (0.47) HSD17B1HSD17B2ESR2MCL1ESR1
SCHEMBL9243488 0.75 TYR (0.58) ALOX5ESR2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476347-B1 Resin compound, resin composition, and resin-molded article FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8476347-B1 Resin compound, resin composition, and resin-molded article FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-20130165565-A1 RESIN COMPOUND, RESIN COMPOSITION, AND RESIN-MOLDED ARTICLE FUJI XEROX CO., LTD. (JP) 2013-06-27 US disclosed
US-20130165565-A1 RESIN COMPOUND, RESIN COMPOSITION, AND RESIN-MOLDED ARTICLE FUJI XEROX CO., LTD. (JP) 2013-06-27 US disclosed