⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23748439 | 0.81 | — | — | |
| SCHEMBL3286933 | 0.79 | — | — | |
| SCHEMBL7067758 | 0.78 | ACHE (0.50) | — | |
| SCHEMBL15300932 | 0.77 | — | — | |
| SCHEMBL21638952 | 0.75 | — | — | |
| SCHEMBL394175 | 0.75 | — | — | |
| SCHEMBL14721793 | 0.75 | — | — | |
| SCHEMBL19142615 | 0.73 | — | — | |
| SCHEMBL19136728 | 0.73 | — | — | |
| SCHEMBL7716083 | 0.72 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058380-A1 | Novel aminobenzophenone compounds | OTTOSEN ERIK R | 2006-03-16 | — | — | US | claimed |
| EP-4364727-A2 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | Teon Therapeutics, Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| EP-3762386-B1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |
| US-20220056033-A1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-9340531-B2 | Cycloalkyl-substituted imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-17 | — | — | US | disclosed |
| US-9340531-B2 | Cycloalkyl-substituted imidazole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-05-17 | — | — | US | disclosed |
| US-8946144-B2 | Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections | THE MEDICINES COMPANY (US) | 2015-02-03 | — | — | US | disclosed |
| US-8946144-B2 | Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections | THE MEDICINES COMPANY (US) | 2015-02-03 | — | — | US | disclosed |
| US-8901072-B2 | Glycopeptide and lipoglycopeptide antibiotics with improved solubility | THE MEDICINES COMPANY (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901072-B2 | Glycopeptide and lipoglycopeptide antibiotics with improved solubility | THE MEDICINES COMPANY (US) | 2014-12-02 | — | — | US | disclosed |
| US-20050137174-A1 | Prodrugs of 9-aminomethyl tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2005-06-23 | — | — | US | disclosed |
| US-6897236-B1 | Aminobenzophenones as inhibitors of IL-1β and TNF-α | LEO PHARMACEUTICAL PRODUCTS, LTD. (DK) | 2005-05-24 | — | — | US | disclosed |
| WO-2005028473-A1 | ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2005009944-A1 | PRODRUGS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| EP-1202959-B1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1-BETA AND TNF-ALPHA | LEO PHARMA AS (DK) | 2004-09-29 | — | — | EP | disclosed |
| US-20030008814-A1 | Pseudomycin phosphate prodrugs | ELI LILLY AND COMPANY | 2003-01-09 | — | — | US | disclosed |
| EP-1202959-A1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1-BETA AND TNF-ALPHA | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |
| WO-2001041534-A2 | PSEUDOMYCIN PHOSPHATE PRODRUGS | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |
| WO-2001005749-A1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1β AND TNF-$g(a) | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-01-25 | — | — | WO | disclosed |