Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426702 | 0.98 | NPC1 (0.50) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL2729578 | 0.98 | KDM4E (0.54) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL2729098 | 0.93 | KDM4E (0.50) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL2718884 | 0.92 | KDM4E (0.53) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL2729335 | 0.89 | NPC1 (0.57) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL21312049 | 0.86 | KDM4E (0.48) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL12974154 | 0.85 | KDM4E (0.45) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL10299039 | 0.85 | SMN1; SMN2 (0.51) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL10299341 | 0.85 | PIM1 (0.46) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL4651756 | 0.83 | NPC1 (0.52) | KDM4EKMT2ANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014011483-A1 | OXADIAZOLE AND TRIAZOLE META-LINKED N-PHENYL CARBAZOLE AMBIPOLAR HOST MATERIALS | GEORGIA TECH RESEARCH CORPORATION (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-2013096921-A1 | NON-CROSSLINKED POLYSTYRENE TRISCARBAZOLE HOLE TRANSPORT MATERIALS | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-06-27 | — | — | WO | disclosed |