Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729578 | 0.94 | KDM4E (0.54) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL15426702 | 0.92 | NPC1 (0.50) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL15074716 | 0.92 | KDM4E (0.52) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL2729335 | 0.90 | NPC1 (0.57) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL2729098 | 0.90 | KDM4E (0.50) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL12974154 | 0.88 | KDM4E (0.45) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL10299040 | 0.87 | SMN1; SMN2 (0.50) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL10299380 | 0.87 | PIM1 (0.45) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL15435102 | 0.86 | HPGD (0.41) | KDM4EKMT2ANPC1RAB9AHPGD | |
| SCHEMBL10299365 | 0.86 | PTK2 (0.42) | KDM4EKMT2ANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569311-B1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RES INST (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2569311-B1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RES INST (US) | 2016-01-13 | — | — | EP | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2569311-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | Georgia Tech Research Corporation (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| WO-2012088316-A1 | 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-2445905-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | Georgia Tech Research Corporation (US) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149620-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149622-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149622-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149618-A1 | POLYMERIC AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149618-A1 | POLYMERIC AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149620-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD1, OCIAD2, OXA1L | KDM4E 4762/4885KMT2A 4517/4885NPC1 643/4885 |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD2, OCIAD1, ORC3 | KDM4E 4027/4885KMT2A 3651/4885NPC1 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.