Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718884 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL15426702 | 0.85 | NPC1 (0.50) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL15074716 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2729578 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2729335 | 0.82 | NPC1 (0.57) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2729098 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10299040 | 0.77 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10299380 | 0.77 | PIM1 (0.45) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL17281773 | 0.76 | L3MBTL1 (0.47) | KDM4EALDH1A1HPGDKMT2AALOX5 | |
| SCHEMBL10299365 | 0.76 | PTK2 (0.42) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149622-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149618-A1 | POLYMERIC AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149620-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |