Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077459 | 0.85 | MAPK14 (0.42) | ALDH1A1FDPSMAPK14 | |
| SCHEMBL29628230 | 0.74 | FDPS (0.49) | ALDH1A1GLAFDPSHPGDTSHR | |
| SCHEMBL4605658 | 0.73 | PDE4B (0.41) | ALDH1A1FDPSMEN1POLBHPGD | |
| SCHEMBL1545332 | 0.72 | FDPS (0.63) | ALDH1A1FDPSMEN1POLBHPGD | |
| SCHEMBL11595224 | 0.72 | ALDH1A1 (0.55) | ALDH1A1GLAFDPSMEN1HPGD | |
| SCHEMBL26750471 | 0.72 | ALDH1A1 (0.55) | ALDH1A1GLAFDPSMEN1HPGD | |
| SCHEMBL26750481 | 0.72 | ALDH1A1 (0.55) | ALDH1A1GLAFDPSMEN1HPGD | |
| SCHEMBL24328600 | 0.71 | FDPS (0.43) | ALDH1A1GLAFDPSPOLBTSHR | |
| SCHEMBL24329411 | 0.71 | FDPS (0.43) | ALDH1A1GLAFDPSPOLBTSHR | |
| SCHEMBL24328789 | 0.71 | FDPS (0.43) | ALDH1A1GLAFDPSPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093615-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | MICURX PHARMACEUTICALS, INC. (KY) | 2013-06-27 | — | — | WO | disclosed |