Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075308 | 1.00 | CYP2C9 (0.40) | CYP2C9ALDH1A1L3MBTL1TSHRMETAP2 | |
| SCHEMBL15075309 | 1.00 | CYP2C9 (0.40) | CYP2C9ALDH1A1L3MBTL1TSHRMETAP2 | |
| SCHEMBL28777363 | 0.86 | CYP2C9 (0.40) | CYP2C9ALDH1A1L3MBTL1TSHRMETAP2 | |
| SCHEMBL15071513 | 0.84 | CYP2C9 (0.39) | CYP2C9ALDH1A1L3MBTL1TSHRMETAP2 | |
| SCHEMBL15071511 | 0.84 | CYP2C9 (0.39) | CYP2C9ALDH1A1L3MBTL1TSHRMETAP2 | |
| SCHEMBL15071516 | 0.84 | CYP2C9 (0.39) | CYP2C9ALDH1A1L3MBTL1TSHRMETAP2 | |
| SCHEMBL6850448 | 0.83 | ALDH1A1 (0.51) | CYP2C9ALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL6777811 | 0.83 | ALDH1A1 (0.51) | CYP2C9ALDH1A1L3MBTL1TSHRGAA | |
| Hydrochloric Acid SCHEMBL6777810 | 0.81 | ALDH1A1 (0.50) | CYP2C9ALDH1A1L3MBTL1TSHRGAA | |
| Hydrochloric Acid SCHEMBL6777809 | 0.81 | ALDH1A1 (0.50) | CYP2C9ALDH1A1L3MBTL1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605018-B2 | Substituted nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150141363-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. | 2015-05-21 | — | — | US | disclosed |
| US-8980865-B2 | Substituted nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20130164261-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130164261-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | PNP, NUDT1, TYMP | CYP2C9 4386/4885ALDH1A1 2567/4885L3MBTL1 388/4885 |
| US-20150141363-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | PNP, NUDT1, TYMP | CYP2C9 4386/4885ALDH1A1 2567/4885L3MBTL1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.