Xanthine

Xanthine

SCHEMBL1507586

O=c1[nH]c(=O)c2[nH]cnc2[nH]1.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 3/20 0.96
ACHE P22303 1/20 0.96
ABL1 P00519 1/20 0.47
RIN1 Q13671 1/20 0.47
ADORA2B P29275 6/20 0.46
ADORA2A P29274 3/20 0.46
ALDH1A1 P00352 2/20 0.45
PNP P00491 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
PDE4A P27815 2/20 0.42
PDE4B Q07343 2/20 0.42
PDE4C Q08493 2/20 0.42
PDE4D Q08499 2/20 0.42
ADORA3 P0DMS8 5/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
GRIA4 P48058 1/20 0.40
USP2 O75604 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthine SCHEMBL27923402 1.00 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL29669592 0.98 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL2352524 0.98 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL4965 0.98 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL2454001 0.96 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL31152020 0.96 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL31048830 0.96 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7044227 0.96 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7849418 0.96 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7044230 0.96 GDA (0.96) GDAACHEABL1RIN1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074972-A1 Artificial Vitreous Humor for the Investigation of Drugs and Drug Formulations HOFFMANN-LA ROCHE INC. (US) 2024-03-07 US claimed
CN-111278426-B Artificial vitreous humor for research of drugs and pharmaceutical preparations 豪夫迈·罗氏有限公司 2023-08-04 CN claimed
CN-111254109-B Method for in vitro fertilization and embryo culture of bovine oocytes and transport culture solution 天津力牧生物科技有限公司 2022-07-08 CN claimed
CN-113201484-B Method for improving cryopreservation and thawing of bovine in vitro fertilization blastocysts 天津力牧生物科技有限公司 2022-05-27 CN claimed
CN-112501114-B Method for improving cattle in-vitro fertilization efficiency 天津力牧生物科技有限公司 2022-05-27 CN claimed
CN-113151160-B Method for improving cattle in-vitro fertilization efficiency and used freezing medium and thawing medium 天津力牧生物科技有限公司 2022-05-13 CN claimed
CN-108728404-B Method for culturing in vitro fertilization embryo of bovine living body or in vitro collected oocyte 天津博裕力牧科技有限公司 2021-09-10 CN claimed
CN-108728401-B Method for culturing bovine oocyte in vitro fertilization embryo and used culture medium 天津博裕力牧科技有限公司 2021-09-10 CN claimed
CN-108753689-B Method for culturing bovine in-vitro fertilized embryo 天津博裕力牧科技有限公司 2021-09-07 CN claimed
CN-113201484-A Method for improving cryopreservation and thawing of bovine in vitro fertilization blastocysts 天津博裕力牧科技有限公司 2021-08-03 CN claimed
CN-109943522-A A kind of mammalian in vitro fertilization Embryo Culture method 南京鼓楼医院 2019-06-28 CN claimed
EP-3476384-A1 ARTIFICIAL VITREOUS HUMOR FOR THE INVESTIGATION OF DRUGS AND DRUG FORMULATIONS F. Hoffmann-La Roche AG (CH) 2019-05-01 EP claimed
CN-108753689-A The method of ox IVF Embryos culture 天津博裕力牧科技有限公司 2018-11-06 CN claimed
CN-108728401-A The method of IVF of Oocyte in Bovine Embryo Culture and culture medium used 天津博裕力牧科技有限公司 2018-11-02 CN claimed
CN-108728404-A Ox live body or the method for in vitro oocyte collection IVF Embryos culture 天津博裕力牧科技有限公司 2018-11-02 CN claimed
CN-108686212-A The method for producing the drug of the method and screening of hyperuricemia animal model for treating hyperuricemia 中国农业科学院农产品加工研究所 2018-10-23 CN claimed
CN-101182490-A Culture medium used for Vero cell and cultivation method thereof TIAN JIN BIOROC PHARMACEUTICAL (CN) 2008-05-21 CN claimed
CN-1657604-A Preparation and using method of culture medium HUANG ZONGTANG (CN) 2005-08-24 CN claimed
EP-0304004-B1 Process for the production of sodium purines BOEHRINGER INGELHEIM KG (DE) 1993-11-03 EP claimed
EP-0304004-A1 Process for the production of sodium purines BOEHRINGER INGELHEIM KG (DE) 1989-02-22 EP claimed