Xanthine

Xanthine

SCHEMBL2352524

O=c1[nH]c(=O)c2[nH]cnc2[nH]1.O=c1[nH]c(=O)c2[nH]cnc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 3/20 1.00
ACHE P22303 1/20 1.00
ABL1 P00519 1/20 0.48
RIN1 Q13671 1/20 0.48
ADORA2B P29275 6/20 0.47
ADORA2A P29274 3/20 0.47
ALDH1A1 P00352 2/20 0.46
PNP P00491 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PDE4A P27815 2/20 0.43
PDE4B Q07343 2/20 0.43
PDE4C Q08493 2/20 0.43
PDE4D Q08499 2/20 0.43
ADORA3 P0DMS8 5/20 0.41
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
PTGS1 P23219 1/20 0.40
MAPK3 P27361 1/20 0.40
XDH P47989 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthine SCHEMBL4965 1.00 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL29669592 1.00 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL31152020 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7044230 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL31048830 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL2454001 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL1507586 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7044227 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7849418 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL6783299 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180707-A Fluorescence probe and its preparation method and application for detecting xanthine 辽宁大学 2019-01-11 CN claimed
CN-117229980-B Weissella sinica fermented feed and application and deodorization effect thereof 北京市农林科学院 2024-01-30 CN disclosed
CN-117229980-A Weissella sinica fermented feed and application and deodorization effect thereof 北京市农林科学院 2023-12-15 CN disclosed
CN-110384770-A Lemon grass extract and preparation method thereof for treating gout 文小燕 2019-10-29 CN disclosed
CN-105218479-B The new derivatives, preparation method and application of 2- [3- cyano-4-isobutoxy phenyl] -4- methylthiazol-5-formic acid 湘北威尔曼制药股份有限公司 2019-10-25 CN disclosed
CN-107573365-B A kind of double copper complex dicopper complex4-amino-3s and preparation method with SOD enzyme activity 广西师范大学 2019-10-15 CN disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-109983119-A GLYCOENGINEERING OF E-SELECTIN LIGANDS 罗伯特·萨克斯坦 2019-07-05 CN disclosed
CN-105272984-B Pyrazolo [3,4-d] pyrimidin-4-one-derivatives, preparation method and application 湘北威尔曼制药股份有限公司 2019-06-14 CN disclosed
CN-106470981-B The new derivatives, preparation method and application of 2- [3- cyano-4-isobutoxy phenyl] -4- methylthiazol-5-formic acid 湘北威尔曼制药股份有限公司 2019-05-07 CN disclosed
EP-0070656-B1 IMMOBILIZED SUPEROXIDE DISMUTASE, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION Takeda Chemical Industries, Ltd. (JP) 1986-09-24 EP disclosed
US-4563349-A WATER-SOLUBLE POLYSACCHARIDE CARRIER TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-01-07 US disclosed
US-4454228-A Biologically pure culture of Streptomyces microspinus NRRL 12524 capable of producing antibiotic U-64,815 THE UPJOHN COMPANY (US) 1984-06-12 US disclosed
US-4427776-A CULTURING STREPTOMYCES MICROSPINUS TO PRODUCE ANTIBIOTIC U-64,815 THE UPJOHN COMPANY (US) 1984-01-24 US disclosed
EP-0070656-A2 Immobilized superoxide dismutase, its production and pharmaceutical composition Takeda Chemical Industries, Ltd. (JP) 1983-01-26 EP disclosed
US-4338319-A 3-ETHYLXANTHINE AKTIEBOLAGET DRACO (SE) 1982-07-06 US disclosed
EP-0045222-A2 Mn-Superoxide dismutase, its production and use Takeda Chemical Industries, Ltd. (JP) 1982-02-03 EP disclosed
US-4310627-A ANTIBIOTIC CULTURES THE UPJOHN COMPANY (US) 1982-01-12 US disclosed
US-4136171-A ANTIBIOTIC 354 AND PROCESS FOR PRODUCING SAME THE UPJOHN COMPANY (US) 1979-01-23 US disclosed
US-4113855-A ANTIBIOTICS, SULFATE SALT THE UPJOHN COMPANY (US) 1978-09-12 US disclosed