Xanthine

Xanthine

SCHEMBL4965

O=c1[nH]c(=O)c2[nH]cnc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 3/20 1.00
ACHE P22303 1/20 1.00
ABL1 P00519 1/20 0.48
RIN1 Q13671 1/20 0.48
ADORA2B P29275 6/20 0.47
ADORA2A P29274 3/20 0.47
ALDH1A1 P00352 2/20 0.46
PNP P00491 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PDE4A P27815 2/20 0.43
PDE4B Q07343 2/20 0.43
PDE4C Q08493 2/20 0.43
PDE4D Q08499 2/20 0.43
ADORA3 P0DMS8 5/20 0.41
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
PTGS1 P23219 1/20 0.40
MAPK3 P27361 1/20 0.40
XDH P47989 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthine SCHEMBL29669592 1.00 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL2352524 1.00 GDA (1.00) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL31152020 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7044230 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL31048830 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL2454001 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL1507586 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7044227 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL7849418 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B
Xanthine SCHEMBL6783299 0.98 GDA (0.96) GDAACHEABL1RIN1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 120165 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
CN-122081155-A Pediococcus acidilactici TC-4 capable of degrading nucleoside, purine and uric acid simultaneously and application thereof 2026-05-26 CN claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US claimed
US-20260137652-A1 Composition Comprising Non-Phosphorylated Tryptamine SINTALICA S R L (IT) 2026-05-21 US claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
US-20260138935-A1 System and method for the production of chemical compounds and nutrient optimized fertilizer from animal waste products Nalari Scientific, LLC (US) 2026-05-21 US claimed
US-4189469-A Pharmaceutical compositions HOECHST AKTIENGESELLSCHAFT (DE) 1980-02-19 US claimed
EP-0001735-A1 Xanthine derivatives having antiallergic activity and pharmacological preparations containing them Aktiebolaget DRACO (SE) 1979-05-02 EP claimed
US-4141976-A XANTHINES OR THIOXANTHINES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1979-02-27 US claimed
US-4120947-A Xanthine compounds and method of treating bronchospastic and allergic diseases COOPER LABORATORIES, INC. (US) 1978-10-17 US claimed
US-4113282-A TETRANITRODIPHENYL ACETIC ACID DERIVATIVES THE MEAD CORPORATION (US) 1978-09-12 US claimed
US-4105656-A PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US claimed
US-4089959-A Long-acting xanthine bronchodilators and antiallergy agents COOPER LABORATORIES, INC. (US) 1978-05-16 US claimed
US-3977944-A Enzyme-kinetic determination of the concentration of a substrate EPPENDORF GERATEBAU NETHELER & HINZ GMBH (DT) 1976-08-31 US claimed
US-3954663-A EXTRACTION, XANTHINE DERIVATIVES TEIKOKU HORININE MFG. CO. LTD. (JA) 1976-05-04 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed