Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076015 | 1.00 | MEN1 (0.69) | MEN1KMT2AALDH1A1HPGDGPR139 | |
| SCHEMBL15076019 | 1.00 | MEN1 (0.69) | MEN1KMT2AALDH1A1HPGDGPR139 | |
| SCHEMBL20535150 | 0.84 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HPGDGPR139 | |
| SCHEMBL5929946 | 0.84 | TSHR (0.57) | MEN1KMT2AALDH1A1HPGDATM | |
| SCHEMBL15075994 | 0.83 | POLB (0.59) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL15075993 | 0.83 | POLB (0.59) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL15076001 | 0.83 | POLB (0.59) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL28615060 | 0.83 | POLB (0.59) | MEN1KMT2AALDH1A1HPGDGPR139 | |
| SCHEMBL10033935 | 0.82 | MEN1 (0.70) | MEN1KMT2AALDH1A1HPGDACP3 | |
| SCHEMBL12158734 | 0.82 | MEN1 (0.66) | MEN1KMT2AALDH1A1HPGDGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092979-A1 | ALPHA-AMINO BORONIC ACID DERIVATIVES, SELECTIVE IMMUNOPROTEASOME INHIBITORS | ARES TRADING S.A. (CH) | 2013-06-27 | — | — | WO | disclosed |