Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | OGT | O15294 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076015 | 0.84 | MEN1 (0.69) | ALDH1A1HPGDMEN1KMT2AACP3 | |
| SCHEMBL15076017 | 0.84 | MEN1 (0.69) | ALDH1A1HPGDMEN1KMT2AACP3 | |
| SCHEMBL15076019 | 0.84 | MEN1 (0.69) | ALDH1A1HPGDMEN1KMT2AACP3 | |
| SCHEMBL4990705 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDFFAR1MEN1KMT2A | |
| SCHEMBL27909941 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDMEN1KMT2AACP3 | |
| SCHEMBL1913816 | 0.82 | CACNA2D1 (0.47) | ALDH1A1HPGDFFAR1MEN1KMT2A | |
| SCHEMBL30514317 | 0.82 | CACNA2D1 (0.47) | ALDH1A1HPGDFFAR1MEN1KMT2A | |
| SCHEMBL14691472 | 0.82 | MEN1 (0.54) | ALDH1A1HPGDFFAR1MEN1KMT2A | |
| SCHEMBL3188356 | 0.81 | MEN1 (0.53) | MEN1KMT2AACP3CTSAADRB2 | |
| SCHEMBL3658103 | 0.81 | HIF1A (0.50) | ALDH1A1HPGDFFAR1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189011-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |