SCHEMBL1507679

SCHEMBL1507679

O=C1c2ccc(O)cc2C(=O)c2c1ccc(O)c2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 1.00
MEN1 O00255 6/20 0.70
MAPT P10636 6/20 0.70
KMT2A Q03164 6/20 0.70
MCL1 Q07820 6/20 0.70
MAOA P21397 5/20 0.70
BCL2 P10415 5/20 0.70
ALDH1A1 P00352 4/20 0.70
MAPK1 P28482 4/20 0.70
KDM4E B2RXH2 3/20 0.70
CYP3A4 P08684 3/20 0.70
HPGD P15428 3/20 0.70
ALOX15 P16050 3/20 0.70
RECQL P46063 3/20 0.70
HSD17B10 Q99714 3/20 0.70
APEX1 P27695 2/20 0.70
ALOX12 P18054 2/20 0.70
DAPK1 P53355 2/20 0.70
CYP1B1 Q16678 2/20 0.70
SMN1; SMN2 Q16637 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30695846 1.00 TTR (1.00) TTRMEN1MAPTKMT2AMCL1
SCHEMBL30695849 1.00 TTR (1.00) TTRMEN1MAPTKMT2AMCL1
SCHEMBL1495097 1.00 TTR (1.00) TTRMEN1MAPTKMT2AMCL1
Quinalizarin SCHEMBL6746696 0.91 TTR (0.82) TTRMEN1MAPTKMT2AMCL1
SCHEMBL9350283 0.86 TTR (0.76) TTRMEN1MAPTKMT2AMCL1
SCHEMBL29543816 0.86 TTR (0.75) TTRMEN1MAPTKMT2AMCL1
SCHEMBL13064957 0.85 TTR (0.74) TTRMEN1MAPTKMT2AMCL1
SCHEMBL6906327 0.84 TTR (0.72) TTRMEN1MAPTKMT2AMCL1
SCHEMBL2772226 0.84 MAPT (0.86) TTRMEN1MAPTKMT2AMCL1
Athraquinones A SCHEMBL18614 0.82 MAPT (1.00) TTRMEN1MAPTKMT2AMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021042001-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC (US) 2021-03-04 WO claimed
WO-2015134969-A1 OPTIMIZED SYNTHETIC RECEPTORS FOR THE DETECTION OF ANALYTES IN COMPLEX WATER-BASED MEDIA BEACON SCIENCES, LLC (US) 2015-09-11 WO claimed
US-7846628-B2 Hole blocking layer containing photoconductors XEROX CORPORATION (US) 2010-12-07 US claimed
US-5877210-A CONTROLLING IMMUNE RESPONSE BRISTOL-MYERS SQUIBB COMPANY (US) 1999-03-02 US claimed
EP-0878480-A1 A method for the improvement of neuronal regeneration Müller, H.W., Prof. Dr. (DE) 1998-11-18 EP claimed
US-5583242-A VANADYL COMPLEXES BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-10 US claimed
US-5565491-A FOR TREATMENT OF DISEASES MARKED BY MALIGNANT PROLIFERATION OF B CELLS, SUCH AS LEUKEMIA AND LYMPHOMAS; ANTICARCINOGENIC AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-15 US claimed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
US-5064442-A HAIR DYES L'OREAL (FR) 1991-11-12 US claimed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO claimed
US-4602913-A Use of hydroxyanthraquinones for the coloration of human keratin fibres L'OREAL (FR) 1986-07-29 US claimed
US-4425404-A MULTILAYER, PROTECTIVE COATINGS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-01-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB TTR 2423/4885MEN1 1711/4885MAPT 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.