SCHEMBL6906327

SCHEMBL6906327

O=C1c2ccc(O)cc2C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.72
MAOA P21397 6/20 0.71
ESR2 Q92731 6/20 0.71
ESR1 P03372 5/20 0.71
MAOB P27338 2/20 0.71
UGT1A1 P22309 1/20 0.71
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
MAPT P10636 4/20 0.61
HPGD P15428 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
KDM4E B2RXH2 3/20 0.55
ALDH1A1 P00352 3/20 0.55
CYP3A4 P08684 3/20 0.55
ALOX15 P16050 3/20 0.55
MAPK1 P28482 3/20 0.55
RECQL P46063 3/20 0.55
HSD17B10 Q99714 3/20 0.55
APEX1 P27695 2/20 0.55
BRCA1 P38398 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthraflavicacid SCHEMBL28102629 0.92 MAOA (0.70) TTRMAOAESR2ESR1MAOB
SCHEMBL30695849 0.84 TTR (1.00) TTRMAOAESR2ESR1MAOB
SCHEMBL1507679 0.84 TTR (1.00) TTRMAOAESR2ESR1MAOB
SCHEMBL6904810 0.84 MAOA (0.70) TTRMAOAESR2ESR1MAOB
SCHEMBL30695846 0.84 TTR (1.00) TTRMAOAESR2ESR1MAOB
SCHEMBL1495097 0.84 TTR (1.00) TTRMAOAESR2ESR1MAOB
Anthraflavicacid SCHEMBL29985684 0.84 ESR2 (1.00) TTRMAOAESR2ESR1MAOB
Anthraflavicacid SCHEMBL31105422 0.84 ESR2 (1.00) TTRMAOAESR2ESR1MAOB
SCHEMBL2772476 0.84 ESR2 (1.00) TTRMAOAESR2ESR1MAOB
Anthraflavicacid SCHEMBL124974 0.84 ESR2 (1.00) TTRMAOAESR2ESR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP claimed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP disclosed
CN-107847466-B Formulations and methods for modulating wound healing 贝欧曼蒂克丝公司 2024-02-06 CN disclosed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20210228501-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2021-07-29 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10426742-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2019-10-01 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20190022029-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2019-01-24 US disclosed
US-20160296477-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2016-10-13 US disclosed
WO-2016164531-A2 FORMULATION AND PROCESS FOR MODULATING WOUND HEALING BioMendics, LLC (US) 2016-10-13 WO disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed
EP-0320227-B1 Method of preventing polymer-scale formation SHINETSU CHEMICAL CO (JP) 1994-09-07 EP disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed
EP-0137262-B1 MONO- AND BIFUNCTIONAL ANTHRAQUINONE-(OXY-2,3-OXIDOPROPANES), METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICINES HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-15 EP disclosed
US-4762648-A ADRENERGIC BLOCKING AGENTS, CROSSLINKING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
EP-0137262-A1 Mono- and bifunctional anthraquinone-(oxy-2,3-oxidopropanes), method for their preparation and their use as medicines HOECHST AKTIENGESELLSCHAFT (DE) 1985-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB TTR 2797/4885MAOA 4700/4885ESR2 4058/4885
US-20160296477-A1 Formulation and Process for Modulating Wound Healing SQSTM1, ATG7, TFEB TTR 2988/4885MAOA 4676/4885ESR2 4022/4885
US-20210228501-A1 Formulation and Process for Modulating Wound Healing ATG7, SQSTM1, ATF4 TTR 2045/4885MAOA 4389/4885ESR2 4242/4885
US-10426742-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB TTR 2797/4885MAOA 4700/4885ESR2 4058/4885
US-20190022029-A1 Formulation and Process for Modulating Wound Healing SQSTM1, ATG7, TFEB TTR 2797/4885MAOA 4700/4885ESR2 4058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.