SCHEMBL15076841

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3115682	0.90	HDAC4 (0.42)	SIGMAR1HDAC4DRD2OPRM1OPRD1
	SCHEMBL23231960	0.87	HDAC4 (0.50)	HDAC4OPRM1OPRD1OPRK1OPRL1
	SCHEMBL615903	0.85	SIGMAR1 (0.57)	SIGMAR1HDAC4DRD2OPRM1OPRD1
	SCHEMBL7510607	0.84	DRD2 (0.46)	SIGMAR1HDAC4DRD2OPRM1OPRD1
	SCHEMBL22778198	0.83	HDAC4 (0.51)	HDAC4OPRM1OPRD1OPRK1OPRL1
	SCHEMBL2276508	0.83	SIGMAR1 (0.51)	SIGMAR1HDAC4DRD2OPRM1OPRD1
	SCHEMBL2270695	0.83	SIGMAR1 (0.47)	SIGMAR1HDAC4DRD2OPRM1OPRD1
	Ethyne SCHEMBL27599449	0.82	SIGMAR1 (0.54)	SIGMAR1HDAC4DRD2OPRM1OPRD1
	SCHEMBL1329573	0.81	HDAC4 (0.42)	SIGMAR1HDAC4OPRM1OPRD1OPRK1
	SCHEMBL30824567	0.81	HDAC4 (0.42)	SIGMAR1HDAC4OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.