SCHEMBL1507770

SCHEMBL1507770

Fc1c(I)ccc(Br)c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2487490 0.81 KDM1A (0.39)
SCHEMBL30906668 0.79
SCHEMBL8979083 0.79
SCHEMBL22289292 0.75 NOTUM (0.39)
SCHEMBL22289786 0.75 NOTUM (0.34)
SCHEMBL30784392 0.75 IMPDH2 (0.31)
SCHEMBL13429845 0.75 KDM1A (0.31)
SCHEMBL22864465 0.75
SCHEMBL31045668 0.75 CHEK1 (0.32)
SCHEMBL30384641 0.75 NOTUM (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103980098-B Containing difluoromethoxy ether bridged bond (CF2The preparation method of monomer liquid crystal compound O) 上海康鹏化学有限公司 2016-07-13 CN disclosed
EP-2295421-B2 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2016-04-06 EP disclosed
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
EP-2295421-B1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2013-02-20 EP disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed
EP-2295421-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2011-03-16 EP disclosed
US-20100001636-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-01-07 US disclosed