Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289786 | 1.00 | NOTUM (0.34) | NOTUMHTR2AHTR2CHTR2B | |
| SCHEMBL30384989 | 0.83 | NOTUM (0.40) | NOTUM | |
| SCHEMBL17711300 | 0.83 | NOTUM (0.40) | NOTUM | |
| SCHEMBL29509555 | 0.77 | NOTUM (0.38) | NOTUMHTR2AHTR2CHTR2B | |
| SCHEMBL17709972 | 0.77 | NOTUM (0.38) | NOTUMHTR2AHTR2CHTR2B | |
| SCHEMBL2487490 | 0.77 | KDM1A (0.39) | — | |
| SCHEMBL23486898 | 0.75 | NOTUM (0.37) | NOTUMHTR2AHTR2CHTR2B | |
| SCHEMBL9339526 | 0.75 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL1507770 | 0.75 | — | — | |
| SCHEMBL31384112 | 0.75 | HTR2A (0.32) | NOTUMHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642778-A1 | LSD1 MODULATORS | Recursion Pharmaceuticals, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12421211-B2 | Heterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240368117-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-11-07 | — | — | US | disclosed |
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |
| US-11858912-B2 | Heterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230337531-A1 | NOVEL COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230133845-A1 | NOVEL HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230337531-A1 | NOVEL COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CRY1, AHR, CRY2 | NOTUM 4015/4885HTR2A 659/4885HTR2C 215/4885 |
| US-11858912-B2 | Heterocyclic compounds | F12, C1R, MRPL21 | NOTUM 4180/4885HTR2A 3065/4885HTR2C 1893/4885 |
| US-12421211-B2 | Heterocyclic compounds | F12, C1R, MRPL21 | NOTUM 4180/4885HTR2A 3065/4885HTR2C 1893/4885 |
| US-20230133845-A1 | NOVEL HETEROCYCLIC COMPOUNDS | F12, PM20D2, XDH | NOTUM 4216/4885HTR2A 3387/4885HTR2C 2291/4885 |
| US-20240368117-A1 | HETEROCYCLIC COMPOUNDS | F12, C1R, MRPL21 | NOTUM 4180/4885HTR2A 3065/4885HTR2C 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.