Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27118826 | 0.90 | RXFP1 (0.46) | RXFP1SLC13A3MAPTCCR2GPR35 | |
| SCHEMBL788007 | 0.85 | SLC13A3 (0.43) | RXFP1SLC13A3MAPTCCR2GPR35 | |
| SCHEMBL27969948 | 0.84 | SLC13A3 (0.46) | RXFP1SLC13A3MAPTCCR2GPR35 | |
| SCHEMBL8574413 | 0.83 | MAPT (0.57) | RXFP1SLC13A3MAPTGPR35ALDH1A1 | |
| SCHEMBL15077304 | 0.83 | CYP17A1 (0.40) | CYP17A1TOP2ATOP2BCYP1A2 | |
| SCHEMBL6815815 | 0.82 | RXFP1 (0.44) | RXFP1SLC13A3MAPTCCR2GPR35 | |
| SCHEMBL14793217 | 0.82 | RXFP1 (0.44) | RXFP1SLC13A3MAPTCCR2GPR35 | |
| SCHEMBL12475072 | 0.81 | GPR35 (0.49) | MAPTTAAR1GPR35ALDH1A1LMNA | |
| SCHEMBL687306 | 0.80 | RXFP1 (0.48) | RXFP1SLC13A3MAPTCCR2GPR35 | |
| SCHEMBL7075937 | 0.79 | ALDH1A1 (0.43) | RXFP1SLC13A3MAPTCCR2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165440-A1 | JAK1 Inhibitors | EXELIXIS, INC. (US) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165440-A1 | JAK1 Inhibitors | JAK1, JAK2, JAK3 | RXFP1 147/4885SLC13A3 4323/4885MAPT 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.