Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077772 | 0.74 | CACNA2D1 (0.44) | ALDH1A1KDM4ECYP1A2CYP2C19PABPC1 | |
| SCHEMBL15077740 | 0.71 | CYP1A2 (0.41) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29213040 | 0.70 | MAPT (0.41) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29213002 | 0.69 | CACNA2D1 (0.40) | ALDH1A1KDM4ECYP1A2CYP2C19PABPC1 | |
| SCHEMBL29213035 | 0.69 | NR1H2 (0.35) | ALDH1A1KDM4EPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL29212985 | 0.66 | CACNA2D1 (0.40) | ALDH1A1KDM4ECYP1A2CYP2C19PABPC1 | |
| SCHEMBL10054127 | 0.66 | CYP2C19 (0.40) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3573293 | 0.66 | APP (0.48) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| Propane SCHEMBL27957403 | 0.64 | CYP2C19 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KCNN4 | |
| SCHEMBL734904 | 0.63 | DHFR (0.41) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206100-B2 | Route to synthetic analogues of Rocaglamide and Aglafoline using cascade transformations initiated by oxy-cope rearrangement of bis-alkynes | The Florida State University Research Foundation, Inc. (US) | 2015-12-08 | — | — | US | disclosed |
| US-20130165683-A1 | NEW ROUTE TO SYNTHETIC ANALOGUES OF ROCAGLAMIDE AND AGLAFOLINE USING CASCADE TRANSFORMATIONS INITIATED BY OXY-COPE REARRANGEMENT OF BIS-ALKYNES | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION INC. | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165683-A1 | NEW ROUTE TO SYNTHETIC ANALOGUES OF ROCAGLAMIDE AND AGLAFOLINE USING CASCADE TRANSFORMATIONS INITIATED BY OXY-COPE REARRANGEMENT OF BIS-ALKYNES | COASY, RIMKLA, ACSL3 | ALDH1A1 1262/4885KDM4E 3581/4885CYP1A2 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.