Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978738 | 0.77 | PTK2 (0.48) | L3MBTL1PTK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21394879 | 0.77 | GSK3B (0.40) | ABL1MAP4K1 | |
| SCHEMBL21757902 | 0.72 | — | — | |
| SCHEMBL8328931 | 0.70 | L3MBTL1 (0.59) | L3MBTL1ABL1PTK2PIK3C3CRBN | |
| SCHEMBL29311778 | 0.70 | — | — | |
| SCHEMBL15601633 | 0.68 | TDP1 (0.34) | NPC1RAB9AFGFR1GAA | |
| SCHEMBL19073506 | 0.68 | KDM4E (0.43) | SMN1; SMN2 | |
| SCHEMBL30755633 | 0.67 | AAK1 (0.44) | L3MBTL1ABL1PTK2PIK3C3NPC1 | |
| SCHEMBL20861632 | 0.67 | L3MBTL1 (0.53) | L3MBTL1ABL1PTK2PIK3C3CRBN | |
| SCHEMBL20772436 | 0.67 | L3MBTL1 (0.53) | L3MBTL1ABL1PTK2PIK3C3CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096630-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |