Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FSHR | P23945 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005881 | 0.79 | BCL2 (0.41) | GSK3BDYRK1ALCKBCL2MAPK1 | |
| SCHEMBL12225872 | 0.78 | GSK3B (0.48) | GSK3BDYRK1ALCKAAK1MAPK1 | |
| SCHEMBL5908666 | 0.77 | GSK3B (0.46) | GSK3BDYRK1ALCKAAK1MAPK1 | |
| SCHEMBL15079563 | 0.77 | L3MBTL1 (0.40) | ABL1MAP4K1 | |
| SCHEMBL26125387 | 0.74 | GSK3B (0.46) | GSK3BDYRK1ALCKAAK1MAPK1 | |
| SCHEMBL30298062 | 0.74 | GSK3B (0.46) | GSK3BDYRK1ALCKAAK1MAPK1 | |
| SCHEMBL30107231 | 0.74 | GSK3B (0.46) | GSK3BDYRK1ALCKBCL2AAK1 | |
| SCHEMBL16905389 | 0.74 | GSK3B (0.46) | GSK3BDYRK1ALCKBCL2AAK1 | |
| SCHEMBL25345910 | 0.73 | GSK3B (0.45) | GSK3BDYRK1ALCKAAK1MAPK1 | |
| SCHEMBL16753674 | 0.73 | GSK3B (0.45) | GSK3BDYRK1ALCKAAK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |