Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613172 | 0.91 | GPR35 (0.55) | GPR35CA2SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL255379 | 0.88 | GPR35 (0.52) | GPR35LMNAKCNK2KCNK4CA2 | |
| SCHEMBL137698 | 0.88 | GPR35 (0.52) | GPR35LMNACA2RORCCCNE1 | |
| SCHEMBL140432 | 0.88 | GPR35 (0.52) | GPR35LMNAKCNK2KCNK4CA2 | |
| SCHEMBL17861117 | 0.88 | GPR35 (0.52) | GPR35LMNACA2RORCCCNE1 | |
| SCHEMBL17861116 | 0.87 | GPR35 (0.52) | GPR35LMNAKCNK2KCNK4CA2 | |
| SCHEMBL140675 | 0.87 | GPR35 (0.52) | GPR35LMNAKCNK2KCNK4CA2 | |
| SCHEMBL13996323 | 0.83 | GPR35 (0.62) | GPR35LMNACA2SMN1; SMN2KDM4E | |
| SCHEMBL12652606 | 0.83 | GPR35 (0.51) | GPR35LMNACA2RORCSMN1; SMN2 | |
| SCHEMBL17861142 | 0.83 | GPR35 (0.51) | GPR35LMNACA2RORCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476450-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2013-07-02 | — | — | US | disclosed |