Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861116 | 1.00 | GPR35 (0.52) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL255379 | 0.94 | GPR35 (0.52) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL140432 | 0.94 | GPR35 (0.52) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17856889 | 0.94 | GPR35 (0.43) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17861115 | 0.90 | GPR35 (0.54) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL140402 | 0.90 | GPR35 (0.54) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12312891 | 0.88 | GPR35 (0.52) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17861053 | 0.88 | GPR35 (0.52) | GPR35MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17861143 | 0.87 | GPR35 (0.52) | GPR35MAPTMEN1KMT2ALMNA | |
| SCHEMBL17856888 | 0.87 | GPR35 (0.43) | GPR35MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030503-A1 | OXIDIZED GLUTATHIONE ASSAY | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-02-01 | — | — | US | disclosed |
| US-9816127-B2 | Oxidized glutathione assay | PROMEGA CORPORATION (US) | 2017-11-14 | — | — | US | disclosed |
| US-9816127-B2 | Oxidized glutathione assay | PROMEGA CORPORATION (US) | 2017-11-14 | — | — | US | disclosed |
| EP-2611929-B1 | OXIDIZED GLUTATHIONE ASSAY | PROMEGA CORP (US) | 2016-01-13 | — | — | EP | disclosed |
| US-20120058501-A1 | OXIDIZED GLUTATHIONE ASSAY | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2012-03-08 | — | — | US | disclosed |
| WO-2012030960-A1 | OXIDIZED GLUTATHIONE ASSAY | PROMEGA CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |
| US-7951550-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2011-05-31 | — | — | US | disclosed |
| EP-2277872-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2272972-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | GPR35 3523/4885MAPT 4279/4885ALDH1A1 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.