Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | CFB | P00751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946224 | 0.89 | SLC6A2 (0.42) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL6945398 | 0.84 | SLC6A2 (0.52) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL15080463 | 0.78 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15080462 | 0.74 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL7969941 | 0.74 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL13444094 | 0.72 | SLC6A4 (0.65) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL7961378 | 0.70 | SLC6A2 (0.39) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL6953668 | 0.70 | SLC6A4 (0.65) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL6946493 | 0.69 | SLC6A2 (0.49) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL15046983 | 0.65 | SLC6A2 (0.63) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |