Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618634 | 1.00 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL16247231 | 0.93 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL19455910 | 0.93 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL23416462 | 0.93 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL19660999 | 0.93 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL15080493 | 0.92 | — | — | |
| SCHEMBL15080485 | 0.92 | — | — | |
| SCHEMBL14765442 | 0.91 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL15080735 | 0.89 | ABCB1 (0.30) | ABCB1 | |
| SCHEMBL15604384 | 0.86 | ABCB1 (0.32) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476451-B2 | Tubulysin D analogues | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110263650-A1 | Tubulysin D Analogues | HELMHOLTZ-ZENTRUM FÜR INFEKTIONS-FORSCHUNG GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263650-A1 | Tubulysin D Analogues | NGLY1, TEKT1, TEK | ABCB1 2787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.