Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23416462 | 1.00 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL19455910 | 1.00 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL19660999 | 1.00 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL17190077 | 0.93 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL14983997 | 0.93 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL17083027 | 0.93 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL13618634 | 0.93 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL15604384 | 0.93 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL14983992 | 0.93 | ABCB1 (0.32) | ABCB1CYP1A2CYP2C19 | |
| SCHEMBL15080494 | 0.93 | ABCB1 (0.32) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360950-A1 | DRUG DELIVERY CONJUGATES CONTAINING UNNATURAL AMINO ACIDS AND METHODS FOR USING | ENDOCYTE INC (US) | 2017-12-21 | — | — | US | disclosed |
| US-9505747-B2 | Processes for preparing tubulysin derivatives and conjugates thereof | ENDOCYTE, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9499849-B2 | Processes for preparing tubulysins | ENDOCYTE, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160177363-A1 | PROCESSES FOR PREPARING TUBULYSINS | ENDOCYTE INC (US) | 2016-06-23 | — | — | US | disclosed |
| US-9273091-B2 | Processes for preparing tubulysins | ENDOCYTE, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150225447-A1 | PROCESSES FOR PREPARING TUBULYSINS | ENDOCYTE, INC. (US) | 2015-08-13 | — | — | US | disclosed |
| US-20150051399-A1 | PROCESSES FOR PREPARING TUBULYSIN DERIVATIVES AND CONJUGATES THEREOF | ENDOCYTE, INC. | 2015-02-19 | — | — | US | disclosed |
| US-8889880-B2 | Processes for preparing tubulysins | ENDOCYTE, INC. (US) | 2014-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360950-A1 | DRUG DELIVERY CONJUGATES CONTAINING UNNATURAL AMINO ACIDS AND METHODS FOR USING | SLC7A1, SLC1A5, DNPEP | ABCB1 192/4885CYP1A2 4811/4885CYP2C19 4622/4885 |
| US-20150225447-A1 | PROCESSES FOR PREPARING TUBULYSINS | NGLY1, LGMN, TEKT1 | ABCB1 2967/4885CYP1A2 4735/4885CYP2C19 4623/4885 |
| US-20150051399-A1 | PROCESSES FOR PREPARING TUBULYSIN DERIVATIVES AND CONJUGATES THEREOF | TEK, C3AR1, TEKT1 | ABCB1 2869/4885CYP1A2 4129/4885CYP2C19 4057/4885 |
| US-20160177363-A1 | PROCESSES FOR PREPARING TUBULYSINS | NGLY1, LGMN, TEKT1 | ABCB1 2967/4885CYP1A2 4735/4885CYP2C19 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.