Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936281 | 0.86 | MRGPRX4 (0.57) | MRGPRX4PPARAPPARGPPARDMMP2 | |
| SCHEMBL1508062 | 0.80 | PPARA (0.53) | MRGPRX4PPARAPPARGPPARDMMP2 | |
| SCHEMBL1508056 | 0.77 | FFAR1 (0.48) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL13462733 | 0.76 | MRGPRX4 (0.58) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL3959702 | 0.76 | TRPM8 (0.48) | PPARAPPARGPPARD | |
| SCHEMBL4451913 | 0.74 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL5385604 | 0.74 | PPARA (0.68) | PPARAPPARGPPARDMAOBFFAR1 | |
| SCHEMBL5365342 | 0.74 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL13819475 | 0.74 | MRGPRX4 (0.59) | MRGPRX4PPARAPPARGPPARDMAOB | |
| SCHEMBL3375496 | 0.73 | MRGPRX4 (0.62) | MRGPRX4MMP2MMP9MMP14ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |