SCHEMBL15080915

SCHEMBL15080915

CCCOc1ccc(-c2ccc(OCC)c(F)c2F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
CASP7 P55210 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.38
CSNK2A1 P68400 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16855831 0.96 MAPT (0.43) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL16855848 0.91 L3MBTL1 (0.47) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL29444871 0.91 CYP1A2 (0.42) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL16855828 0.91 CYP1A2 (0.42) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL29444864 0.91 L3MBTL1 (0.47) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL16855852 0.90 L3MBTL1 (0.42) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL15682056 0.89 FPR2 (0.40) L3MBTL1TDP1MAPTKDM4EMEN1
SCHEMBL19450271 0.88 MAPT (0.48) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL16852422 0.87 AAK1 (0.38) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL16855833 0.86 CYP1A2 (0.44) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150175884-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-25 US disclosed
US-8475679-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-07-02 US disclosed