Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15080943 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CES2CES1LNPEPERAP2 | |
| SCHEMBL12142616 | 0.83 | SLC7A5 (0.57) | ALDH1A1CES2CES1PTGS2TPH1 | |
| SCHEMBL3736020 | 0.83 | SLC7A5 (0.57) | ALDH1A1CES2CES1PTGS2TPH1 | |
| SCHEMBL7333309 | 0.83 | KMT2A (0.50) | ALDH1A1LNPEPERAP2ESR1ESR2 | |
| SCHEMBL15080987 | 0.83 | KMT2A (0.50) | ALDH1A1LNPEPERAP2ESR1ESR2 | |
| SCHEMBL15080989 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LNPEPERAP2ESR1ESR2 | |
| SCHEMBL15019652 | 0.81 | LOXL2 (0.59) | ALDH1A1LNPEPERAP2SLC7A5LOXL2 | |
| Hydrochloric Acid SCHEMBL30947772 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LNPEPERAP2ESR1ESR2 | |
| SCHEMBL2059174 | 0.81 | ANPEP (0.54) | ALDH1A1LNPEPERAP2ESR1ESR2 | |
| SCHEMBL15019650 | 0.81 | LOXL2 (0.59) | ALDH1A1LNPEPERAP2SLC7A5LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476411-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-07-02 | — | — | US | disclosed |