Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12673428 | 0.88 | ALDH1A1 (0.47) | ALDH1A1ERAP2LNPEPESR1ESR2 | |
| SCHEMBL15081046 | 0.88 | ALDH1A1 (0.47) | ALDH1A1ERAP2LNPEPESR1ESR2 | |
| SCHEMBL15080945 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2ESR1ESR2 | |
| SCHEMBL12142783 | 0.83 | SLC7A5 (0.57) | ALDH1A1KDM4ESMN1; SMN2PTGS2TPH1 | |
| SCHEMBL15080987 | 0.83 | KMT2A (0.50) | ALDH1A1HPGDSMN1; SMN2ERAP2LNPEP | |
| SCHEMBL7333309 | 0.83 | KMT2A (0.50) | ALDH1A1HPGDSMN1; SMN2ERAP2LNPEP | |
| SCHEMBL2059174 | 0.81 | ANPEP (0.54) | ALDH1A1SMN1; SMN2ERAP2LNPEPESR1 | |
| Hydrochloric Acid SCHEMBL30947772 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2ERAP2LNPEP | |
| SCHEMBL15019652 | 0.81 | LOXL2 (0.59) | ALDH1A1KDM4EHPGDSMN1; SMN2ERAP2 | |
| SCHEMBL15019650 | 0.81 | LOXL2 (0.59) | ALDH1A1KDM4EHPGDSMN1; SMN2ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476411-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-07-02 | — | — | US | disclosed |