Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143574 | 0.87 | SLC7A5 (0.42) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL12673691 | 0.81 | SLC7A5 (0.34) | GRIK1GRIK2IDO1TDO2ALPI | |
| SCHEMBL15081000 | 0.81 | SLC7A5 (0.34) | GRIK1GRIK2IDO1TDO2ALPI | |
| SCHEMBL11981444 | 0.78 | KCNA5 (0.35) | GRIK1GRIK2IDO1TDO2 | |
| SCHEMBL12834546 | 0.78 | GRIK1 (0.31) | GRIK1GRIK2IDO1TDO2ALPI | |
| SCHEMBL18833749 | 0.78 | GRIK1 (0.34) | GRIK1GRIK2ALPIPKMPTGS1 | |
| SCHEMBL14189093 | 0.75 | ALPI (0.38) | GRIK1GRIK2IDO1TDO2ALPI | |
| SCHEMBL12208676 | 0.75 | ALPI (0.38) | GRIK1GRIK2IDO1TDO2ALPI | |
| SCHEMBL12160508 | 0.75 | KMO (0.34) | GRIK1GRIK2 | |
| SCHEMBL14959877 | 0.74 | IDO1 (0.32) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476411-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-07-02 | — | — | US | disclosed |