Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081021 | 0.85 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL15081013 | 0.85 | ALDH1A1 (0.30) | — | |
| SCHEMBL27256473 | 0.81 | SLC7A5 (0.40) | GRIK1GRIK2SLC7A5 | |
| SCHEMBL7841366 | 0.80 | GRIK1 (0.30) | GRIK1GRIK2 | |
| SCHEMBL12673691 | 0.80 | SLC7A5 (0.34) | GRIK1GRIK2SLC7A5ALPIPKM | |
| SCHEMBL15081000 | 0.80 | SLC7A5 (0.34) | GRIK1GRIK2SLC7A5ALPIPKM | |
| SCHEMBL11981444 | 0.79 | KCNA5 (0.35) | GRIK1GRIK2 | |
| SCHEMBL15081037 | 0.78 | GRIK1 (0.32) | GRIK1GRIK2SLC7A5ALPIPKM | |
| SCHEMBL15080996 | 0.77 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL14434562 | 0.77 | ITGB2 (0.34) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217265-B1 | MODIFIED INSULIN POLYPEPTIDES AND THEIR USES | AMBRX INC (US) | 2017-05-10 | — | — | EP | disclosed |