Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508214 | 0.80 | ACHE (0.36) | KCNN4RAB9AUSP2CYP19A1CA1 | |
| SCHEMBL1508127 | 0.80 | KCNN4 (0.40) | KCNN4RAB9AUSP2CYP19A1CA1 | |
| SCHEMBL1508050 | 0.75 | HSD11B1 (0.33) | KCNN4RAB9AUSP2HSD11B1ACHE | |
| SCHEMBL1508035 | 0.75 | HSD11B1 (0.33) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL1508204 | 0.73 | MAPK1 (0.37) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL1507934 | 0.73 | KCNN4 (0.39) | KCNN4RAB9AUSP2NPC1MAPT | |
| SCHEMBL1507912 | 0.69 | NPC1 (0.37) | RAB9ACYP19A1HSD11B1NPC1KMT2A | |
| SCHEMBL14066322 | 0.69 | KCNN4 (0.40) | KCNN4SMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL1507904 | 0.69 | KMT2A (0.37) | KCNN4RAB9AACHESMN1; SMN2MEN1 | |
| SCHEMBL1507940 | 0.69 | KCNN4 (0.40) | KCNN4RAB9ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292595-A1 | Potassium channel modulators | NeuroSearch AS (DK) | 2011-03-09 | — | — | EP | disclosed |