Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.50 |
| ▸ | ITGAV | P06756 | 4/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | NNMT | P40261 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879247 | 0.90 | CACNA1B (0.50) | CACNA1BITGB3ITGA2BITGAVITGB1 | |
| SCHEMBL29359881 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7743802 | 0.84 | ITGB3 (0.56) | CACNA1BITGB3ITGA2BITGAVITGB1 | |
| SCHEMBL22807631 | 0.83 | CACNA1B (0.57) | CACNA1BITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL8365733 | 0.82 | ITGB3 (0.53) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL25455154 | 0.82 | CACNA1B (0.61) | CACNA1BITGB3ITGAVITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL29973120 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL25474158 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL19605549 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL19605449 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BITGAVITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160017000-A1 | RGD-CONTAINING CYCLIC PEPTIDES | UNIV CALIFORNIA (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160017000-A1 | RGD-CONTAINING CYCLIC PEPTIDES | UNIV CALIFORNIA (US) | 2016-01-21 | — | — | US | disclosed |
| US-9073974-B2 | RGD-containing cyclic peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-07 | — | — | US | disclosed |
| US-9073974-B2 | RGD-containing cyclic peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130172270-A1 | RGD-CONTAINING CYCLIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172270-A1 | RGD-CONTAINING CYCLIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160017000-A1 | RGD-CONTAINING CYCLIC PEPTIDES | ITGAV, ITGB3, ITGAL | CACNA1B 1817/4885ITGB3 2/4885ITGA2B 10/4885 |
| US-20130172270-A1 | RGD-CONTAINING CYCLIC PEPTIDES | ITGAV, ITGB3, ITGAL | CACNA1B 1817/4885ITGB3 2/4885ITGA2B 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.