Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL1508698 | 0.80 | TUBB1 (0.42) | ALDH1A1L3MBTL1KDM4ECYP3A4 | |
| Combretastatin SCHEMBL6429900 | 0.77 | TUBB1 (0.65) | MAPK1CYP1A2CYP1A1CYP1B1GAA | |
| SCHEMBL296731 | 0.74 | TUBB1 (0.64) | GAA | |
| SCHEMBL28654468 | 0.72 | TUBB1 (0.48) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL28659072 | 0.71 | TUBB1 (0.47) | ALDH1A1L3MBTL1KDM4E | |
| Niacinamide SCHEMBL5672506 | 0.68 | F7 (0.71) | GAAMKNK1MKNK2ALDH1A1F7 | |
| SCHEMBL13991618 | 0.68 | TUBB4A (0.61) | ALDH1A1KDM4ERXFP1 | |
| SCHEMBL10882130 | 0.67 | MAPK1 (0.65) | MAPK1CYP1A2CYP1A1CYP1B1GAA | |
| SCHEMBL1508665 | 0.66 | TUBB1 (0.58) | GAA | |
| SCHEMBL30061143 | 0.65 | MAPK1 (0.64) | MAPK1GAATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289521-A2 | Compositions and methods for use in tergeting vascular destruction | ARIZONA BOARD OF REGENTS (US) | 2011-03-02 | — | — | EP | claimed |