SCHEMBL15083012

SCHEMBL15083012

C[C@H](O)Cc1c(Cl)cccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TAAR1 Q96RJ0 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
POLB P06746 1/20 0.41
DRD2 P14416 2/20 0.40
DRD3 P35462 2/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
GAA P10253 1/20 0.38
OPRK1 P41145 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
NFKB1 P19838 1/20 0.38
PNMT P11086 1/20 0.38
HTT P42858 1/20 0.37
TSHR P16473 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2426412 1.00 AKR1B1 (0.43) AKR1B1SMN1; SMN2TAAR1ALDH1A1HPGD
SCHEMBL2423264 0.86 AKR1B1 (0.37) AKR1B1SMN1; SMN2TAAR1ALDH1A1HPGD
SCHEMBL2428955 0.86 GAA (0.53) SMN1; SMN2TAAR1ALDH1A1HPGDGAA
SCHEMBL2423583 0.83 P2RX7 (0.44) AKR1B1GAASLC6A2SLC6A4L3MBTL1
SCHEMBL5018858 0.81 TAAR1 (0.44) AKR1B1SMN1; SMN2TAAR1ALDH1A1HPGD
SCHEMBL9248083 0.80 HPGD (0.36) AKR1B1SMN1; SMN2TAAR1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL9253661 0.79 HPGD (0.35) AKR1B1TAAR1ALDH1A1HPGDPOLB
SCHEMBL16055266 0.78 TRPA1 (0.38) AKR1B1SMN1; SMN2TAAR1ALDH1A1HPGD
SCHEMBL8790684 0.77 TAAR1 (0.46) AKR1B1SMN1; SMN2TAAR1ALDH1A1DRD3
SCHEMBL13692457 0.77 SLC6A2 (0.54) TAAR1ALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 EP disclosed
WO-2013100569-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed