Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 4/20 | 0.34 |
| ▸ | FNTB | P49356 | 4/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23056622 | 1.00 | NOD1 (0.40) | NOD1HDAC2GNPATALDH1A1MAPT | |
| SCHEMBL16289076 | 0.85 | ALDH1A1 (0.38) | NOD1HDAC2GNPATALDH1A1MAPT | |
| SCHEMBL15083216 | 0.85 | ALDH1A1 (0.38) | NOD1HDAC2GNPATALDH1A1MAPT | |
| SCHEMBL7081466 | 0.82 | FNTA (0.50) | HDAC2ALDH1A1FNTAFNTBPGGT1B | |
| SCHEMBL7081469 | 0.82 | FNTA (0.50) | HDAC2ALDH1A1FNTAFNTBPGGT1B | |
| SCHEMBL15083196 | 0.81 | NOD1 (0.46) | NOD1HDAC2GNPATSLC6A5FNTA | |
| SCHEMBL16288853 | 0.81 | NOD1 (0.46) | NOD1HDAC2GNPATSLC6A5FNTA | |
| SCHEMBL15083156 | 0.79 | — | — | |
| SCHEMBL16288400 | 0.79 | — | — | |
| SCHEMBL15083125 | 0.79 | EPHX2 (0.39) | NOD1HDAC2GNPATALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813512-B1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-2813512-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | Chugai Seiyaku Kabushiki Kaisha (JP) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013100132-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | 中外製薬株式会社 (JP) | 2013-07-04 | — | — | WO | disclosed |